Understanding von Willebrand Disease

Von Willebrand disease (vWD) is a genetic bleeding disorder caused by a deficient or defective von Willebrand factor (vWF). vWF is a clotting protein in the blood that binds factor VIII (an essential blood-clotting protein) and platelets in blood vessel walls, which help form a platelet plug during the clotting process. vWD is the most common inherited bleeding disorder in the United States, affecting approximately 1 percent of the U.S. population. It is carried on chromosome 12 and occurs equally in men and women. Learn more about the diagnosis, symptoms, and treatment of vWD below.

This “Patient Education” tear sheet was produced in collaboration with the National Hemophilia Foundation (www.hemophilia.org).

Patient Education: Understanding Von Willebrand Disease

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