Clotting Disorders

Clotting Disorders

A collection of features and news articles published in ASH Clinical News related to clotting disorders.

American Society of Hematology’s Guidelines for Venous Thromboembolism and von Willebrand Disease

In 2018, the American Society of Hematology (ASH) has continued its efforts to develop and publish evidence-based clinical practice guidelines to help practicing hematologists...

Researchers Define Long-Term Outcomes of Cancer-Associated Thrombosis

Patients diagnosed with cancer-associated thrombosis (CAT) remain at a high risk for recurrent venous thromboembolism (VTE), bleeding, and death – even while on therapeutic...

Tumor Site, D-Dimer Markers Predict VTE Risk in Patients With Cancer

Venous thromboembolism (VTE) is a common complication of cancer, with the risk of developing VTE varying greatly depending on several patient and disease factors....
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No Benefit, but Excess Toxicity, With Rivaroxaban for Patients With High-Risk Antiphospholipid Syndrome

Rivaroxaban and other direct oral anticoagulants are used as an alternative to warfarin for the prevention of thromboembolism, but data do not support routine...

How I Treat In Brief: Managing Disseminated Intravascular Coagulation

Recently, Marcel Levi, MD, and Marie Scully, MD, wrote about their strategies for the management of patients with disseminated intravascular coagulation (DIC). Below, we...
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Study Finds Thromboembolism Is a Frequent Complication of ALL Treatment

Adolescents and adults with acute lymphocytic leukemia (ALL) are at a “markedly” increased risk for developing thromboembolism (TE), even when treated according to the...
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Insights From a Pyruvate Kinase Deficiency Registry: Broad Spectrum of Severity, Broad Role for...

No guidelines exist for the diagnosis, management, and monitoring of patients with red cell pyruvate kinase (PK) deficiency – the most common glycolytic defect...

FDA Examining Patient Deaths Associated With Extracorporeal Photopheresis Treatment

The FDA published a letter to health-care providers noting that the CELLEX® Photopheresis System is under review following reports of venous thromboembolism (VTE), including...

Aspirin as Effective as Rivaroxaban for Preventing VTE After Total Hip or Knee Arthroplasty

Standard aspirin is as effective as the newer, direct oral anticoagulant (DOAC) rivaroxaban for preventing venous thromboembolism (VTE) in patients who have undergone total...

A Preview of ASH’s Venous Thromboembolism Clinical Practice Guidelines

In November 2015, the American Society of Hematology (ASH) and the McMaster University GRADE Center announced a collaboration to develop clinical practice guidelines on...
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Current Issue

February 2019, Volume 5, Issue 3

This issue features a look at the unique challenges of developing treatments for orphan diseases, more coverage of the 2018 ASH annual meeting, and more.