Clotting Disorders

A collection of features and news articles published in ASH Clinical News related to clotting disorders.

NIH’s ACTIV Trial Suspends Enrollment of Critically Ill Patients With COVID-19

The National Institutes of Health (NIH) announced that it is pausing enrollment of patients with severe COVID-19 in three trials that are evaluating anticoagulants...
WIB_icon

Is Caplacizumab a Cost-Effective Strategy for Acquired TTP?

In February 2019, the FDA approved the anti–von Willebrand factor immunoglobulin fragment caplacizumab as the only agent specifically indicated for the treatment of adults...
On location

In Utero Hematopoietic Cell Transplantation Safe in Fetuses with Alpha Thalassemia Major

In utero hematopoietic cell transplantation (IUHCT) with maternal cells was safe in two fetuses with alpha thalassemia major (ATM), according to interim results of...
On location

Testing for Inherited Thrombophilias Provides Limited Benefit

Inherited thrombophilias are associated with an increased risk of initial and recurrent venous thromboembolism (VTE), but testing for these conditions in the setting of...

Normal Results on D-Dimer Testing Can Safely Rule out Deep Vein Thrombosis

A simplified approach of an initial stand-alone D-dimer test followed by a single whole-leg compression ultrasound (CUS) in D-dimer positive patients can effectively and...