Bleeding Disorders

Bleeding Disorders

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

FDA Approves New Treatment for Hemophilia

The U.S. Food and Drug Administration (FDA) approved BAY94-9027, or antihemophilic factor (recombinant), PEGylated-aucl, for the prophylactic treatment of adults and adolescents (≥12 years)...

Evaluating Twice-Yearly Denosumab for Transfusion-Dependent, Thalassemia-Induced Osteoporosis

Treatment with twice-yearly denosumab improved spinal bone mineral density (BMD) compared with placebo in patients with transfusion-dependent thalassemia (TDT)–induced osteoporosis, according to results of...

How to Treat Anemia in a Patient Who Refuses Transfusions for Religious Reasons

This month, Neil A. Zakai, MD, discusses how to treat anemia in a patient who refuses packed red blood cells. And don't forget to check out...

How to Treat Anemia in a Patient Who Refuses Transfusions for Religious Reasons

Here’s how readers responded to a You Make the Call question about a Jehovah's Witness patient with stage IV uterine cancer, a uterine abscess,...

FDA Approves DNA-Based Blood Compatibility Test

The U.S. Food and Drug Administration (FDA) has approved ID CORE XT, a molecular-based assay that can be used to determine blood donor and...

FDA Approves New Hemophilia A Drug

The U.S. Food and Drug Administration (FDA) has approved emicizumab-kxwh for the treatment of adult and pediatric patients with hemophilia A without factor VIII...
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Mapping Silent Cerebral Infarcts in Children With Sickle Cell Anemia

Children with sickle cell anemia (SCA) are at risk of developing cerebral ischemia, including a high prevalence of silent cerebral infarcts (SCI), which can...

LentiGlobin Gene Therapy Possibly Safe for Severe Sickle Cell Disease

Interim data from a phase I study of LentiGlobin BB305 in patients with severe sickle cell disease (SCD) suggest that the gene therapy was...

Breakthroughs in Gene Therapy for Hemophilia

Gene therapy for hemophilia is here – and it’s working. The field is advancing at a steady clip: Results from recent trials of this...

How Should We Treat Pregnant Women With Iron Deficiency?

Iron deficiency is prevalent among pregnant women, as maternal iron is used to supply the needs of the fetus and placenta, and additional iron...
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Current Issue

November 2018, Volume 4, Issue 13

This issue features a look at the U.S. drug pricing system, attempts to solve physician burnout, and more.