Red Blood Cell & Iron Disorders

Red Blood Cell & Iron Disorders

A collection of features and news articles published in ASH Clinical News related to red blood cell and iron disorders.

FDA Approves Pegcetacoplan for Paroxysmal Nocturnal Hemoglobinuria

The U.S. Food and Drug Administration (FDA) has approved the targeted C3 inhibitor pegcetacoplan for the treatment of adult patients with paroxysmal nocturnal hemoglobinuria...

More COVID-19 Complications Seen in Black Patients With Sickle Cell Disease and Sickle Cell...

Patients with sickle cell disease (SCD) and sickle cell trait (SCT) have significantly higher rates of hospitalization, pneumonia, and pain related to COVID-19 compared...

Improving Sickle Cell Disease Outcomes in Sub-Saharan Africa Starts With Screening

For patients with sickle cell disease (SCD) living in sub-Saharan Africa, early intervention drastically improves long-term health outcomes, but challenges around funding, training, and...

Beam Therapeutics Develops Inlaid Base Editing Technique for SCD

Beam Therapeutics is testing a new form of CRISPR-based technology called inlaid base editing to modify cells from patients with sickle cell disease (SCD). Base...

Many Children with SCD Not Screened for Stroke Risk

More than 20 years ago, transcranial doppler ultrasounds and blood transfusions were proven to prevent nine out of 10 strokes in children with sickle...

Sickle Cell Trait Cited in Police Custody Deaths

In a review of data on suspicious deaths from more than 30 of the largest U.S. counties, The New York Times found that sickle...

LentiGlobin Not Linked to Cancer, Scientists Say

On February 24, the U.S. Food and Drug Administration (FDA) placed a clinical hold on all LentiGlobin gene therapy trials following an announcement that two participants with...
Sickle cell anemia

First CRISPR Trial for Patients with Severe Sickle Cell Disease to Begin

Scientists at the University of California (UC) Berkeley, the University of California San Francisco (UCSF), and the University of California Los Angeles (UCLA) have...

Transplant Improves Health-Related Quality of Life for Patients With SCD and Transfusion-Dependent Thalassemia

Hematopoietic cell transplantation (HCT) is associated with significant improvements in health-related quality of life (HRQoL) in patients with sickle cell disease (SCD) and transfusion-dependent...

Novartis and the Gates Foundation Collaborate on Off-the-Shelf Gene Therapy for Sickle Cell Disease

Novartis and the Bill and Melinda Gates Foundation are collaborating on a one-step, one-time gene therapy for patients with sickle cell disease (SCD). The...
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Current Issue

June 2021 Volume 7 Issue 7

This issue reviews the management and prevention of peripheral neuropathy, early successes of SCD screening programs in sub-Saharan Africa, and more.

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