Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

A Zebrafish and Enhanced Imaging Captures How Blood Stem Cells Take Root

A research team from Boston Children Hospital’s Stem Cell Research Program has provided the first direct glimpse into how blood stem cells take root...

The Debate Rages on: Is Omitting Radiation Therapy from Hodgkin Lymphoma Good for Patients?

Although Hodgkin lymphoma (HL) is frequently treated with a combination of chemotherapy and radiation therapy, there is a movement towards omitting radiation therapy altogether....

Is It Time to Reconsider Allogeneic SCT in NPM1-Mutant AML?

Allogeneic stem cell transplantation (SCT) significantly improved rates of relapse-free survival (RFS), but not overall survival (OS) in patients with acute myeloid leukemia (AML)...

New Agent PER977 Shows Promise in Reversing Anticoagulation

Although newer target-specific oral anticoagulants represent great advances in the prevention and treatment of blood clots, their use is limited by a lack of effective reversal agents. Severe...

Many Younger Patients Receive Inappropriate First-Line Care

Nearly one-third of adolescent and young adult patients diagnosed with cancer do not receive appropriate therapy, according to recent research published in the Journal of the National Cancer Institute. The...

Panobinostat Improves Survival in Multiple Myeloma: Results from PANORAMA1

A three-drug combination with panobinostat significantly increased median progression-free survival (PFS) in patients with relapsed/refractory multiple myeloma. Adding panobinostat to the multiple myeloma treatment...

Barcoding Stem Cells Add to Understanding of Hematopoietic Disease

A barcoding and tracking system for tissue stem cells has revealed previously unrecognized features of normal blood production: Surprisingly, the billions of blood cells...

New Hope in High-Risk Leukemia Subtype

Philadelphia chromosome-like acute lymphocytic leukemia (Ph-like ALL) is a precursor of B-cell ALL. Unfortunately, pediatric patients with Ph-like ALL face worse outcomes. Adding tyrosine...

The New Normal: Lower Transfusion Thresholds for Septic Shock Patients

A restrictive approach to blood transfusion reduced blood use by half but, more importantly, caused no harm to 998 critically ill patients with septic...

DS-ALL: An Ever-Changing Genetic Mutation Landscape

Children with Down syndrome are at an increased risk for developing leukemia – as much as 50 times more likely than other children. In...
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Current Issue

May 2021 Volume 7 Issue 6

This issue provides an update on gene therapies in hematology, demystifies RNA sequencing, and more.

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