Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

Germline Mutation in Leukemia Highlights Disease Complexity

A recent report published in Nature Genetics has underscored the key role that the ETV6 gene plays in platelet formation and leukemia predisposition.1 Researchers...

Serum Free Light Chain Measurement Has Prognostic Value in All Stages of Myeloma

A normalized serum free light chain (sFLC) ratio in multiple myeloma treatment following a complete response has been tied to better survival. For those...

Corticosteroids Increase the Risk of Recurrent Thrombotic Events

Patients with chronic inflammatory diseases, such as chronic obstructive pulmonary disease and asthma, are already at an increased risk for developing a first pulmonary...

Clonal Evolution: In Aplastic Anemia, Which Mutations Matter?

Mutations in a specific set of genes may predict whether patients with aplastic anemia develop hematologic malignancies, according to research recently published in The New...

New Blood or Old: Do Storage Times of Red Blood Cells Impact Patient Outcomes?

Red blood cells (RBCs) undergo numerous changes as they are stored – some of which may impair their ability to increase oxygen delivery, which...

MRD Levels Mid-Remission: The Key to Better Prognosis for ALL Patients?

(MRD) that persists following remission induction chemotherapy afor acute lymphocytic leukemia (ALL) is a powerful prognostic factor, new research shows that determining MRD levels...

A New Era for Waldenström’s Macroglobulinemia Treatment

In the more than 70 years since Jan G. Waldenström discovered Waldenström's macroglobulinemia, there have been few answers about what causes the malignant B-cell...

High-Cost Surveillance Imaging Falls Short on Survival Benefit in DLBCL

Surveillance imaging to monitor patients with diffuse large B-cell lymphoma (DLBCL) in first remission may be common practice, but a new cost-effectiveness analysis has...

How Costly is Febrile Neutropenia in Patients with Metastatic Cancer?

Febrile neutropenia (FN) is a frequent and often costly complication for patients with metastatic cancer receiving myelosuppressive chemotherapy. When patients develop FN, the likelihood...

Ruxolitinib: Another Option for Polycythemia Vera Patients with Poor RESPONSE

Patients with polycythemia vera who do not respond well to hydroxyurea may have another promising treatment option, according to results from the RESPONSE trial. A...
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Current Issue

Mid-January 2021 Annual Meeting Edition

This issue features highlights from the 2020 ASH Annual Meeting, a look at doctor-patient gifting customs around the world, and more.

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