Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

Many Younger Patients Receive Inappropriate First-Line Care

Nearly one-third of adolescent and young adult patients diagnosed with cancer do not receive appropriate therapy, according to recent research published in the Journal of the National Cancer Institute. The...

Panobinostat Improves Survival in Multiple Myeloma: Results from PANORAMA1

A three-drug combination with panobinostat significantly increased median progression-free survival (PFS) in patients with relapsed/refractory multiple myeloma. Adding panobinostat to the multiple myeloma treatment...

Barcoding Stem Cells Add to Understanding of Hematopoietic Disease

A barcoding and tracking system for tissue stem cells has revealed previously unrecognized features of normal blood production: Surprisingly, the billions of blood cells...

New Hope in High-Risk Leukemia Subtype

Philadelphia chromosome-like acute lymphocytic leukemia (Ph-like ALL) is a precursor of B-cell ALL. Unfortunately, pediatric patients with Ph-like ALL face worse outcomes. Adding tyrosine...

The New Normal: Lower Transfusion Thresholds for Septic Shock Patients

A restrictive approach to blood transfusion reduced blood use by half but, more importantly, caused no harm to 998 critically ill patients with septic...

DS-ALL: An Ever-Changing Genetic Mutation Landscape

Children with Down syndrome are at an increased risk for developing leukemia – as much as 50 times more likely than other children. In...

Good, But Not Optimal – HSCT Match Possible for Most Patients

For patients with certain blood cancers or other diseases, hematopoietic stem cell transplants (HSCT) are potentially lifesaving therapies. While the majority of patients are...

Ruxolitinib Shows Promise in Polycythemia Vera

Ruxolitinib, a JAK1/2 inhibitor approved by the FDA for the treatment of myelofibrosis, also has activity in another myeloproliferative neoplasm, polycythemia vera, according to...
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Current Issue

August 2019, Volume 5, Issue 10

August 2019, Volume 5, Issue 10

This issue features a debate about gun control as a health care issue, a look at blood services in Israel and Palestine, and more.