Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

ALCYONE Update: Adding Daratumumab to VMP Improves Survival in Transplant-Ineligible Myeloma

In patients with newly diagnosed multiple myeloma (MM) who are ineligible for high-dose chemotherapy and transplantation, adding daratumumab to bortezomib, melphalan, and prednisone (VMP)...

Lenalidomide Treatment Delays Progression From Smoldering to Symptomatic Myeloma

Observation is the standard approach to managing most patients with smoldering multiple myeloma (MM), but results from a phase III study suggest that early...

Early Intensification of Intrathecal Chemotherapy Reduces Risk of Relapse in Pediatric ALL

Two additional doses of intrathecal therapy early during induction treatment for children with newly diagnosed acute lymphocytic leukemia (ALL) who were at increased risk...

Post-Induction CVD Chemotherapy Improves PFS in Patients With Newly Diagnosed Myeloma

For patients with newly diagnosed multiple myeloma (MM) who had a suboptimal response to immunomodulatory drug-based induction therapy, intensification treatment with cyclophosphamide, bortezomib, and...

How Does Chemotherapy During Pregnancy Affect Outcomes in Patients With Hodgkin Lymphoma?

In patients diagnosed with Hodgkin lymphoma (HL) during pregnancy, antenatal chemotherapy is associated with increased preterm contractions and lower birthweight for newborns, according to...

Chemotherapy-Free Regimen of ATRA Plus Arsenic Trioxide Improves Survival in APL

Updated results from the APL0406 study suggest that the combination of all-trans retinoic acid (ATRA) plus arsenic trioxide (ATO) was associated with greater long-term...

Vitamin D Deficiency Associated With Poorer Survival in Hodgkin Lymphoma

For patients with Hodgkin lymphoma (HL), having vitamin D deficiency prior to starting treatment appears to be associated with worse progression-free survival (PFS) and...

Is the Flu Vaccine Effective in Patients With Cancer?

In a population-based study published in the Journal of Clinical Oncology, researchers found that the influenza vaccine protected patients with cancer against developing flu,...

Heparin-Induced Thrombocytopenia Does Not Appear to Protect Against Major Bleeding

Patients with heparin-induced thrombocytopenia (HIT), a prothrombotic complication of heparin exposure, are believed to be protected against anticoagulant-associated bleeding, but results from a retrospective analysis...

With PET-Guided Treatment, Can Radiation Be Eliminated in Early-Stage HL?

Combined modality treatment (CMT) consisting of chemotherapy and small-field radiotherapy has long been considered the standard of care for patients with early-stage, favorable Hodgkin...
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January 2020 Annual Meeting Edition

This issue features highlights from the 2019 ASH Annual Meeting, reflections on physician wellness, and more.