Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

Heparin-Induced Thrombocytopenia Does Not Appear to Protect Against Major Bleeding

Patients with heparin-induced thrombocytopenia (HIT), a prothrombotic complication of heparin exposure, are believed to be protected against anticoagulant-associated bleeding, but results from a retrospective analysis...

With PET-Guided Treatment, Can Radiation Be Eliminated in Early-Stage HL?

Combined modality treatment (CMT) consisting of chemotherapy and small-field radiotherapy has long been considered the standard of care for patients with early-stage, favorable Hodgkin...

Case Report Shows CRISPR-Based Gene Editing Feasible for HIV-Infected Patient

In a case study published in the New England Journal of Medicine, researchers successfully used a CRISPR-based gene-editing approach in a patient with HIV...

Cardiovascular Events Common With Proteasome Inhibitor Therapy for Previously Treated Multiple Myeloma

Cardiovascular adverse events (CVAEs) commonly occur during proteasome inhibitor (PI) therapy for relapsed/refractory multiple myeloma (MM), particularly in patients with elevated natriuretic peptides or...

Clofarabine Plus Cytarabine May Provide Less Toxic Option for Newly Diagnosed Pediatric Patients With...

For children newly diagnosed with acute myeloid leukemia (AML), treatment with a combination of clofarabine plus cytarabine was associated with similar survival rates when...

Can ICH Survivors Safely RESTART Antiplatelet Therapy?

While treatment with antiplatelet therapy lessens the risks of subsequent occlusive vascular events, it may increase the risk of recurrent intracerebral hemorrhage (ICH) in...

Roxadustat Improves Hemoglobin Levels and Response Rates in Patients With Anemia Related to Chronic...

According to results from a phase III trial, roxadustat increased hemoglobin levels and hemoglobin response rates, compared with placebo, in patients with anemia and...

Higher Bleeding Risk With Higher Peak Direct Oral Anticoagulant Levels Suggests Need for More...

A study of patients with nonvalvular atrial fibrillation (NVAF) who were receiving a direct oral anticoagulant (DOAC) found that bleeding complications were more frequent...

Male Sex, Factor V Leiden Mutation Increase Recurrent VTE Risk After First Cerebral Venous...

A new study found that male sex and factor V Leiden mutation were associated with a higher risk of recurrent venous thromboembolism (VTE) after...

Testing the Testing Tool: ISTH Bleeding Assessment Accurately Predicts Patients With Platelet Function Disorders

In patients with suspected platelet function disorders, the International Society on Thrombosis and Hemostasis bleeding assessment tool (ISTH-BAT) proved to be a useful instrument...
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