Reduced Calf Muscle Pump Function Predicts VTE and Mortality Risk
Reduced calf pump function (CPF) appears to be a risk factor for venous thromboembolism (VTE), according to a study published in Blood. In addition,...
Adding Brentuximab Vedotin to Chemotherapy Improves Outcomes in Pediatric ALK-Positive ALCL
The addition of brentuximab vedotin to chemotherapy led to favorable overall survival (OS) and event-free survival (EFS) in children with ALK-positive anaplastic large cell...
Lenalidomide and Dexamethasone for Older Patients With Multiple Myeloma: Less Is More
According to a study published in Blood, older patients with multiple myeloma (MM) who are taking continuous lenalidomide-dexamethasone (Rd) may be able to switch...
Outcomes After ABO-Incompatible Platelet Transfusions in Patients With Intracerebral Hemorrhage
For patients with intracerebral hemorrhage (ICH) who received an acute platelet transfusion within 24 hours of hospital admission, the use of an incompatible platelet...
Ixazomib Combination Improves PFS Versus Placebo in Patients With Transplant-Ineligible Myeloma
When researchers added ixazomib to continuous lenalidomide-dexamethasone (Rd) in patients with newly diagnosed, transplant-ineligible multiple myeloma (MM), they observed that the treatment regimen was...
International Working Group Publishes Revised Definitions for Remission, Relapse in Immune TTP
The International Working Group (IWG) for thrombotic thrombocytopenic purpura (TTP) has published revised definitions for response, exacerbation, remission, and relapse of immune-mediated TTP (iTTP)...
Risk of Subsequent Malignant Neoplasms Is Low in Children With Hodgkin Lymphoma
A study published in Blood suggests that children and adolescents with intermediate-risk Hodgkin lymphoma have a relatively low cumulative risk of developing subsequent malignant...
Adults With Hematologic Malignancies and COVID-19 Fare Worse Than Children
Adults with hematologic malignancies and COVID-19 infection have a substantially higher risk of death compared with children with hematologic malignancies and COVID-19, according to...
Avelumab Shows Clinical Activity in Relapsed/Refractory Extranodal Natural Killer/T-Cell Lymphoma
Avelumab is clinically active in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma (ENKTL), although researchers observed a lower-than-expected response rate, according to...
Leukemia Antigen–Specific Donor-Derived T Cells Enhance Graft-Versus-Leukemia Effects in Post-Transplant AML/MDS
For patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) whose disease relapses following a hematopoietic cell transplantation (HCT), unselected donor lymphocytes typically...
Current Issue
May 2021 Volume 7 Issue 6
This issue provides an update on gene therapies in hematology, demystifies RNA sequencing, and more.