Written in Blood

Written in Blood

Research from recent issues of Blood

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Sequential Pembrolizumab and Chemotherapy Results in Excellent Responses in Newly Diagnosed Classical Hodgkin Lymphoma

A brief course of pembrolizumab monotherapy followed by AVD chemotherapy (doxorubicin, vinblastine, and dacarbazine) was associated with reductions in metabolic tumor volume and prolonged...
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PF4-Dependent P-Selectin Assay Highly Accurate in Diagnosing Heparin-Induced Thrombocytopenia

A study published in Blood established the diagnostic accuracy of a PF4-dependent P-selectin expression assay (PEA) for heparin-induced thrombocytopenia (HIT), with a sensitivity similar...
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Is Post-Discharge VTE Prophylaxis Necessary for Patients With COVID-19?

In hospitalized patients with COVID-19, the risk of venous thromboembolism (VTE) following discharge was not significantly greater compared with the VTE risk in patients...
Sickle cell anemia

Hydroxyurea Treatment Before Puberty Does Not Impair Future Sperm Quality in Boys With SCD

Childhood hydroxyurea (hydroxycarbamide) treatment does not impair future sperm parameters in boys with severe sickle cell disease (SCD), according to research published in Blood....
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Mavorixafor Mobilizes White Blood Cells in Patients With WHIM Syndrome

Long-term treatment with once-daily oral mavorixafor, an inhibitor of CXCR4, reduced the number of cutaneous warts and infections and effectively increased neutrophil and lymphocyte...
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Short Telomere Length Increases Non-Relapse Mortality Risk After Allogeneic Transplant for MDS

According to research published in Blood, shorter telomere length was an independent risk factor for non-relapse mortality (NRM) and overall survival (OS) in patients...
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IVIg and Rituximab-Based Regimens Are the Most Effective Treatments for CANOMAD Syndrome

Approximately one-third of patients with CANOMAD (chronic ataxic neuropathy, ophthalmoplegia, immunoglobulin M paraprotein, cold agglutinins, and disialosyl antibodies) syndrome have a hematologic malignancy,...
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Is Haploidentical Better Than Cord Blood Transplantation in Leukemia and Lymphoma?

Allogeneic hematopoietic cell transplantation with cord blood or haploidentical bone marrow extend access to transplantation for patients who lack a human leukocyte antigen (HLA)–matched...
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Small Retrospective Study Suggests Thrombopoietin Receptor Agonists Are Safe, Likely Effective for ITP During...

Preliminary findings from an observational multicenter study suggest that temporary off-label use of thrombopoietin receptor agonists (TPO-RAs) for the treatment of severe and/or refractory...
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ART and PrEP May Present Challenges in Detecting HIV Infection in Blood Donations

While antiretroviral (ARV) drugs and pre-exposure prophylaxis (PrEP) are effective tools to help reduce the burden of HIV, a new study published in Blood...
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November 2020 Bonus ASH Annual Meeting Preview Edition (Volume 6, Issue...

View issue flipbook November 2020 Bonus ASH Annual Meeting Preview Edition Volume 6, Issue 14This issue offers a behind-the-scenes look at this year's virtual annual meeting,...

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