From the Blood Journals

From the Blood Journals

Research from the Blood family of journals: Blood and Blood Advances

Can Dasatinib Overcome the Negative Effects of KIT Mutations in Core Binding Factor AML?

A chemotherapy regimen of cytarabine and daunorubicin plus dasatinib was well tolerated in patients with previously untreated core binding factor acute myeloid leukemia (CBF-AML)...

Metabolic Syndrome Predicts Risk of Recurrent VTE in Patients With Newly Diagnosed DVT

Patients with newly diagnosed deep vein thrombosis (DVT) who have components of metabolic syndrome – hypertension, hyperlipidemia, diabetes mellitus, or obesity – have a...

Higher Altitudes, Higher Hemoglobin: Mapping Switzerland’s Topography and Hemoglobin Levels

Even small increases in residential altitude significantly elevated blood hemoglobin (Hb) and ferritin levels in young men living in Switzerland, according to a study...

Germline RUNX1 Mutations in RUNX1-Mutated AML More Frequent Than Previously Thought

A small study in Canada shows that the frequency of germline RUNX1 mutations in patients with RUNX1-mutated acute myeloid leukemia (AML) is higher than...

Patients With SCD and TP53 Mutations May Develop Myeloid Malignancy After Unsuccessful AlloHCT

Population studies have shown that patients with sickle cell disease (SCD) who have undergone an unsuccessful allogeneic hematopoietic cell transplantation (alloHCT) have an increased...

Blinatumomab Leads to High Remission Rate in Infants With Persistent MRD-Positive ALL

Treatment with the bispecific CD19/CD3 antibody blinatumomab induced molecular remissions in most infants with persistent measurable residual disease (MRD)–positive acute lymphocytic leukemia (ALL), according...

Avadomide Shows Promising Clinical Activity and Tolerability in Relapsed/Refractory DLBCL

Avadomide monotherapy demonstrated preliminary clinical efficacy in patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL), according to results from a phase I...

Peripherally Inserted Central Catheters Sharply Increase Risk of Childhood VTE Events

In children who received central venous catheters, peripherally inserted central catheters (PICCs) appear to be associated with a higher risk of venous thromboembolism (VTE),...

The MAGIC Marker: Measurements of Two Serum Biomarkers Predict GVHD Treatment Response

Measuring damage to crypts in the gastrointestinal tract during graft-versus-host disease (GVHD) via the Mount Sinai Acute GVHD International Consortium (MAGIC) algorithm probability (MAP)...

Early Peripheral Blast Cell Clearance Predicts Response to Induction Chemotherapy in Acute Myeloid Leukemia

Early peripheral blast cell clearance (PBC) assessed by leukocyte differential is well established as a predictor of leukemia induction outcome, but measuring PBC by...

Current Issue

August 2020 Volume 6, Issue 10

This issue looks at the rapid expansion of telemedicine, explores access to leukemia treatment in Brazil, and more.

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