Blood Advances in a Different Vein

Blood Advances in a Different Vein

Research from recent issues of Blood Advances

Post-Transplant High-Dose Chemotherapy Increases Risk of Toxicities in Older Patients With Lymphoma

Most patients with lymphoma who are over age 60 experience cardiovascular toxicities with high-dose chemotherapy and autologous hematopoietic cell transplantation (AHCT), but these patients...

Idelalisib and Obinutuzumab Combination Shows Promise in Relapsed/Refractory Waldenström Macroglobulinemia

A combination regimen consisting of idelalisib and obinutuzumab led to promising response and survival rates in patients with relapsed and refractory Waldenström macroglobulinemia (WM),...

Reduced R-CHOP Intensity Does Not Compromise Survival in Older Patients With DLBCL

Research suggests higher dose intensity R-CHOP (rituximab, cyclophosphamide, doxorubicin hydro-chloride, vincristine sulfate, and prednisone) can improve survival in patients with diffuse large B-cell lymphoma...

Post-Transplant MRD Monitoring With Non-DTA Mutations Predicts Outcomes in AML

In next-generation sequencing (NGS)-based measurable residual disease (MRD) monitoring, the use of non-DNMT3A, TET2, or ASXL1 (non-DTA) mutations may predict relapse and survival following...

Older Patients With Clonal Hematopoiesis and Non-DT Mutations at Higher Risk of Mortality

For patients aged 80 and older, those with clonal hematopoiesis (CH) and mutational spectra other than isolated DNMT3A and TET2 (DT) variants may have...

Extended Thromboprophylaxis Does Not Reduce VTE Incidence in Hospitalized Patients With Cancer

The use of extended thromboprophylaxis with enoxaparin, betrixaban, or rivaroxaban does not reduce the risk of venous thromboembolic (VTE) events in hospitalized patients with...

Does Rheumatic Disease Increase Risk of MGUS Progression to Hematologic Malignancies?

Patients with monoclonal gammopathy of undetermined significance (MGUS) and concomitant non-antibody (Ab)–mediated inflammatory rheumatic diseases are at increased risk of progression to overt multiple...

More COVID-19 Complications Seen in Black Patients With Sickle Cell Disease and Sickle Cell...

Patients with sickle cell disease (SCD) and sickle cell trait (SCT) have significantly higher rates of hospitalization, pneumonia, and pain related to COVID-19 compared...

Tandem High-Dose Influenza Vaccine Offers Durable Seroprotection for Patients With Plasma Cell Dyscrasias

Tandem high-dose influenza vaccination may result in more durable serologic immunity in patients with plasma cell dyscrasias (PCDs), compared with standard vaccination, according to...

Can Caloric Restriction Improve Chemotherapy Response in Overweight Patients With ALL?

Previous reports have found that patients who are overweight or obese during B-cell acute lymphocytic leukemia (B-ALL) induction therapy are at a higher risk...
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Current Issue

October 2021, Volume 7, Issue 12

This issue tells the long story of drug shortages, demystifies transfusion services, and more.

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