Blood Advances in a Different Vein

Blood Advances in a Different Vein

Research from recent issues of Blood Advances

Standardized MRD Assay for FLT3-ITD-Mutated AML Could Guide AML Therapy Decisions

In a report published in Blood Advances, researchers describe a standardized minimal residual disease (MRD) assay that can detect FLT3-ITD mutations in patients with...

DOACs Versus Warfarin in Patients With Cancer and Atrial Fibrillation

Newer direct oral anticoagulants (DOACs) offer an effective alternative to warfarin that does not require monitoring, but these agents are often not recommended in...

Investigating a WT1 Peptide Vaccine in Patients With Acute Myeloid Leukemia

In an open-label, phase II study, treatment with galinpepimut-S (GPS) – a vaccine targeting the Wilms tumor 1 (WT1) protein – was well tolerated...

Understanding Bone Disease and Fractures in Patients With MGUS

Patients with monoclonal gammopathy of undetermined significance (MGUS; a precursor to multiple myeloma and other lymphoproliferative disorders) are known to be at an...

Previous Malignancy May Increase Risk of Subsequent Malignancy in Patients With Myeloma

A number of new treatments for patients with multiple myeloma (MM) have become available in recent years, enabling patients to live longer. Unfortunately, these...

HCT Outcomes in Patients With Autoimmune Diseases Vary With Location, Treatment Center Volume

Hematopoietic cell transplantation (HCT) has been evaluated as a treatment option for patients with autoimmune diseases (ADs) that respond poorly to conventional immunosuppressive treatments...

Patients With CLL Willing to Trade Treatment Efficacy for Reduced Costs and Adverse Events

Some patients living with chronic lymphocytic leukemia (CLL) are willing to accept drugs that are less effective in exchange for reduced adverse events (AEs)...

High Rates of Depression Resulting in Higher Health-Care Costs in Patients With Sickle Cell...

Depression is approximately five times more prevalent in patients with sickle cell disease (SCD) than in the general population, and it is significantly associated...

Study Finds Cancer Risk is Higher Than Expected Among Patients With Pregnancy-Related VTE

Venous thromboembolism (VTE) is associated with an increased prevalence of occult cancer. As pregnancy is also associated with an increased risk of VTE, it...

Low Fetal Hemoglobin May Predict Silent Brain Lesions in Patients With Sickle Cell Disease

Silent white-matter changes (WMC) – permanent neurologic injuries that can cause cognitive deficits and intellectual decline – are common in patients with sickle cell...
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Current Issue

May 2018, Volume 4, Issue 6

This issue features a look at the hidden costs of importing lower-cost drugs, the optimal hemophilia treatment, the limits of genetic testing, and more.