From the Blood Journals

From the Blood Journals

Research from the Blood family of journals: Blood and Blood Advances

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Older Patients with iTTP Have Delayed Diagnosis and Higher Mortality Than Younger Counterparts

Older patients diagnosed with immune thrombotic thrombocytopenic purpura (iTTP) have worse short- and long-term mortality compared with younger patients and the general population, according...
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Eltrombopag Induces Complete Platelet Responses in Patients with Lymphoproliferative Disorders and Treatment-Resistant ITP

Results from a small phase II trial suggest that treatment with eltrombopag was associated with sustained platelet responses and complete responses (CRs) in patients...
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Study Identifies Familial Risk Patterns of Several Hematologic Malignancies

People who have a first-degree relative diagnosed with a hematologic malignancy have a higher risk of developing a blood cancer, according to an analysis...

Pretransplant Bridging With Blinatumomab Reduces MRD in Children With B-Cell Acute Lymphocytic Leukemia

In a study of children with B-cell acute lymphocytic leukemia (B-ALL) who are about to undergo allogeneic hematopoietic cell transplantation (alloHCT), bridging with blinatumomab...
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Pegylated Interferon Leads to High Response Rates in Essential Thrombocythemia and Polycythemia Vera After...

According to results of a phase II study published in Blood, treatment with pegylated-interferon-α (PEG-rIFN-α) was associated with an overall response rate (ORR) of...

Certain Non-Hodgkin Lymphoma Subtypes Carry Higher Risk of Infection-Related Solid Tumor Cancers

Various subtypes of non-Hodgkin lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) and marginal zone lymphoma (MZL), carry a risk for second infection-related solid...
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Estimated Prevalence of JAK2 V617F Mutations High in General Danish Population

The driver mutation JAK2 V617F and Calreticulin (CALR) mutations constitute major diagnostic criteria of myeloproliferative neoplasms (MPNs), and, while JAK2 V617F has been detected...
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Risk of Severe GVHD Lower With Post-Transplant Cyclophosphamide Than ATG in Mismatched Unrelated Donor...

Antithymocyte globulin (ATG) is considered standard graft-versus-host disease (GVHD) prophylaxis in patients with acute myeloid leukemia (AML) who undergo transplantation with a mismatched unrelated...

Can a Patient’s Breath Detect Post-Transplant Gastrointestinal Graft-Versus-Host Disease?

Analyzing the volatile organic compounds (VOCs) expelled in the breath can help clinicians detect and monitor gastrointestinal graft-versus-host disease (GI GVHD) in patients who...
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Short, Aggressive Antibiotic Therapy Inhibits Lymphocyte Proliferation in CTCL

According to a study published in Blood, patients with advanced-stage cutaneous T cell lymphoma (CTCL) a short, yet aggressive, antibiotic regimen inhibited disease activity...
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Current Issue

November 2019, Volume 5, Issue 13

This issue features explores treating older patients with frailty, discusses the management of primary mediastinal B-cell lymphoma, and more.