Meeting News

Meeting News

Pracinostat Added to Azacitidine in Previously Untreated MDS: No Clinical Benefit, But Added Toxicity

Results from a multicenter, placebo-controlled study presented by Guillermo Garcia-Manero, MD, at the ASH annual meeting last month, demonstrated that the oral histone deacetylase...

Genetic Variants Predict Osteonecrosis in Children with ALL

Pediatric patients with acute lymphocytic leukemia (ALL) and chemotherapy-induced osteonecrosis are significantly more likely to possess certain genetic variants near genes essential to bone...

N-Acetylcysteine Increases Platelet Counts in Patients with Thrombotic Thrombocytopenia Purpura

Thrombotic thrombocytopenic purpura (TTP) is a rare hematologic disorder caused by a deficiency of plasma ADAMST13 and systemic microvascular occlusion from von Willebrand factor...

Hemoglobin Modifier GBT440: A New Option for Patients with Sickle Cell Disease

Patients with sickle cell disease (SCD) who received GBT440, a novel oral small molecule hemoglobin modifier, had a reduction in sickle cells, a reduction...

ELOPE: A Look at Patient-Centered Outcomes One Year After Pulmonary Embolism

One year after a pulmonary embolism (PE), patients tend to have less dyspnea, better quality of life (QOL), and improved walking capacity compared to...

Results from the Lumiere Trial: Shining a Light on Alisertib in Relapsed/Refractory PTCL

Patients with relapsed and/or refractory peripheral T-cell lymphoma (PTCL) have limited treatment options, and, subsequently, poor survival outcomes. Alisertib, an investigational oral selective inhibitor...

Brentuximab Vedotin Plus Dacarbazine or Bendamustine: New Options for Older Patients with Hodgkin Lymphoma?

Older patients with Hodgkin lymphoma (HL) often don’t tolerate standard chemotherapy regimens and have worse outcomes compared with younger patients. While previous studies have...

Over-Reporting of At-Home Chemotherapy Adherence Using Self-Reporting Methods: Improving 6MP Maintenance in Pediatric Patients...

Although it is the most convenient method for monitoring oral 6-mercaptopurine (6MP) intake in pediatric patients with acute lymphocytic leukemia (ALL), self-reporting frequently becomes...

Early PET Scans Can Safely Guide Chemotherapy De-Escalation in Patients with Hodgkin Lymphoma

Although escalated BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone), or BEACOPPesc, has been shown to be superior to ABVD chemotherapy in controlling...

Carfilzomib Bests Bortezomib in Relapsed Multiple Myeloma

Results from the phase III, open-label, multicenter ENDEAVOR study support the use of the proteasome inhibitor, carfilzomib, in combination with dexamethasone in patients with...
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Current Issue

September 2019 Volume 5 Issue 11

September 2019, Volume 5, Issue 11

This issue explores politics in the exam room, demystifies proteomic analysis in hematology, and more.