Mikkael Sekeres, MD, MS

    Mikkael Sekeres, MD, MS

    Director of the Leukemia Program at the Cleveland Clinic in Cleveland, Ohio, and editor-in-chief of ASH Clinical News
    • Recommendations from My Bookshelf: A Bloody Mess Monday, October 1st, 2018

      Imagine that you’re young, brilliant, charismatic, and you have a compelling vision for a bold new idea that could revolutionize health care: scores of laboratory tests, from routine chemistries to tests for life-threatening infectious diseases, that could be run on just a few drops of blood from a single finger prick. You even have a [...]

    • Caring About Standards of Care Wednesday, August 1st, 2018

      I’ve been thinking a lot about standards of care recently. A “medical standard of care” is actually a legal term, typically defined as the level and type of care that a reasonably competent and skilled health-care professional, with a similar background and in the same medical community, would have provided under the circumstances that led [...]

    • Tiny Bubbles Monday, May 14th, 2018

      “Double, double toil and trouble; Fire burn and caldron bubble… For a charm of powerful trouble, Like a hell-broth boil and bubble.” William Shakespeare, “Song of the Witches” (from Macbeth)

    • Updates to Our Style Guide for the Sartorially Challenged Sunday, April 1st, 2018

      Every so often, the crackerjack editorial team of ASH Clinical News gets together and discusses style. No, not of the sartorial variety, particularly as mine tends toward chinos, a shirt with a non-asphyxiating collar, and comfortable shoes – matching colors and patterns be damned. This is a combination I like to call “hematologist fashion backwards,” [...]

    • The Good Steward of Science Thursday, February 1st, 2018

      I have participated in a number of clinical trials and database projects with pharmaceutical companies and, as a result, have been an author on a few abstracts and manuscripts with industry as a partner. Truth be told, much of this research has been extremely rewarding, intellectually stimulating, and – most importantly – has advanced care [...]

    • Solving the Contract Research Agonization Problem Friday, December 1st, 2017

      In the June 2017 issue of ASH Clinical News, we published an editorial calling into question some of the purposes and practices of contract research organizations (CROs), which came into existence in the 1980s and are used by much of the pharmaceutical industry to outsource research regulatory requirements. Although CROs – considered specialists in the [...]

    • Meaningful Benefits Friday, September 1st, 2017

      Two roads diverged in a wood, and I – I took the one less traveled by, And that has made all the difference. Robert Frost, “The Road Not Taken”

    • Shouts & Mumblings: A Transplant in Every Kitchen Wednesday, July 5th, 2017

      “Patients with various blood-related cancers … receive transplants of bone marrow and peripheral blood stem cells to restore stem cells that were destroyed by high doses of chemotherapy or radiation therapy or both. After being treated with anti-cancer drugs or radiation, the patient receives the harvested stem cells, which travel to the bone marrow and [...]

    • Contract Research Agonizations Thursday, June 1st, 2017

      After years spent as an investigator on countless hematology and cancer clinical trials, all initiated with the noble intent of improving my patients’ lives through what we all hoped would be better therapies, I have finally arrived at one conclusion that I believe to be virtually unassailable: Contract research organizations (CROs) are an invasive weed [...]

    • Letter From a Cleveland Jail to the ABIM: Patient Practicum Saturday, April 1st, 2017

      Dear American Board of Internal Medicine (ABIM): Writing to you, as usual, from behind the bars of emotional turmoil, political dissonance, and unresolved neuroses regarding K-type questions, hematology reprobate that I am. Like Henry David Thoreau and Martin Luther King Jr., both of whom penned meaningful essays while held captive, I beseech you with my [...]

    • Microphone Moment Wednesday, February 1st, 2017

      Entering Monday’s oral abstract session at the 2016 ASH Annual Meeting, my goals were twofold: to see some great science that may influence how I care for my patients and to support my colleague – a faculty member a couple of years out of fellowship. It wasn’t that long ago (or so I keep telling [...]

    • So You Say You Want To Be A Clinical Researcher? Thursday, December 1st, 2016

      Perhaps you’ve just finished your hematology/oncology fellowship a year or two ago. Or you’re still a fellow and, having completed that intensive first year of inpatient consults and the speed dating outpatient rotations in different specialty clinics, you’ve just woken up to the realization that you have to apply for jobs in a year. Or [...]

    • A Primer on Email Etiquette Saturday, October 1st, 2016

      Every day, more than 200 billion emails are sent and received, for an average of 122 emails sent and received, per user, in a business setting.1 Having just returned from a week of vacation, we believe that approximately all of those 200 billion emails were waiting for us in our inboxes. As we spend increasing [...]

    • Conflict of Conscience Monday, August 1st, 2016

      On the first Wednesday of every month, the Innovation Management and Conflict of Interest Committee at Cleveland Clinic meets to discuss some of the thornier issues that have arisen with our staff members and their relationships with external entities. I am a standing member of this committee, and the majority of our discussions center on [...]

    • Recommendations from My Bookshelf: Cutting for Stone by Abraham Verghese Wednesday, June 1st, 2016

      Have you ever been a stranger in a strange land? I thought I was when I moved from New England to Cleveland, where I had to learn to talk a little slower, and that unfamiliar people who smiled and said “hi” as they passed me in the hallways were not mentally unstable – as I [...]

    • Letter From a Cleveland Jail to the ABIM: MOC Madness Tuesday, March 1st, 2016

      American Board of Internal Medicine Philadelphia, PA March 2016 Dear ABIM, Got your last email. Are you just not that into me anymore? There it sat, an unsightly wart amidst the usual compelling missives occupying my Outlook inbox, with the subject header: “Important update about your certification status.” I opened the message immediately, because you [...]

    • The “Theys” Have It – Or Does He or She? Monday, February 1st, 2016

      Recently, in a decision that was heralded by some as transformative, by others as a “win for gender neutrality,” and by presumably the majority of the U.S. population as entirely irrelevant, the American Dialect Society (come on, you know you’re a member) identified the word “they” as its 2015 Word of the Year, and in [...]

    • Take My Leftover Tissue, Please! Tuesday, December 1st, 2015

      I can understand if maybe you missed the big announcement on September 8. Perhaps you were out apple-picking with your kids, or were getting ready for a hot date that night. Or maybe you failed to scroll through your entire Twitter feed that day. If that’s the case, brace yourself. This is a big one. Years [...]

    • An Unabashed Rehash of the ASH Dash Thursday, October 1st, 2015

      (Or, How to Write an Abstract Guaranteed to be Selected for a Plenary Presentation at the Annual Meeting*) 6:15 a.m. (EST), August 4, 2015: My alarm clock goes off. This is the day: the abstract deadline for the ASH annual meeting. I get out of bed and stand in front of my bedroom mirror to [...]

    • Equal Under the Law Saturday, August 1st, 2015

      What a remarkable couple of months it has been for the law, and for our patients. On Friday, June 26, the highest court in the land ruled that same-sex marriage is a right nationwide. The image that sticks in my mind is The New York Times photograph taken amidst the celebration in front of the [...]

    • A Primer on Conference Call Etiquette Monday, June 1st, 2015

      We’ve all been there. At precisely 2:59 p.m. you pick up the phone handset and dial into the conference call scheduled to start in the next minute. You search through appointment reminders and old emails to find the six-, or seven-, or 10-digit conference code and enter it, followed by the “pound” sign. You wait, [...]

    • Don’t Just Do Something! Stand There. Wednesday, April 1st, 2015

      It’s the hardest thing in the world to do – or not do, as the case may be. Someone has just been diagnosed with cancer. He or she is referred by a primary care doctor to see you. It takes about a week to get an appointment with you, so that person has plenty of [...]

    • Letter From a Cleveland Jail to the ABIM: Redux Sunday, February 1st, 2015

      Dear American Board of Internal Medicine, Remember me? I’m the guy who sent those other letters to you over the past couple of years, in which I channeled the spirits of Henry David Thoreau and Martin Luther King Jr., both of whom wrote passionate epistles while they were in jail — Thoreau for failing to [...]

    • Belonging to a Club That Would Have Me as a Member Monday, December 1st, 2014

      Even though I had practiced my oral presentation a bunch of times, I still cringed when the session moderator announced the abstract number, title, and my name as the presenter, calling me to the stage at precisely 3:45 p.m. No matter how many times you’re fortunate enough to be invited to present your research at [...]

    • A New ASH Publication Dawns Wednesday, October 1st, 2014

      Welcome to the first edition of ASH Clinical News magazine! This new, monthly publication from the American Society of Hematology arose in response to the requests of ASH members and non-members alike for a news magazine dedicated to hematologists/oncologists, nurses and physician assistants, residents, fellows and other trainees, and members of any specialty touched by [...]

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