Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

Can a Post-AHCT, High-Intensity Exercise Program Improve Quality of Life in Patients With Myeloma?

Patients with myeloma who undergo autologous hematopoietic cell transplantation (AHCT) may experience a decline in health-related quality of life (HRQoL). Although exercise has been...

Luspatercept Shows Activity in Patients With Lower-Risk MDS and Anemia

Erythropoiesis-stimulating agents (ESAs) are a standard treatment for patients with myelodysplastic syndromes (MDS) and anemia; however, only around one-third of patients have an erythroid...

Using a Comorbidity-Based Composite Model to Predict Mortality in Patients With AML

Researchers developed a new composite model incorporating patient- and disease-specific features to predict mortality in patients with acute myeloid leukemia (AML), according to a...

Early Evidence Suggests PD-1 Inhibitors May Be Effective in Relapsed/Refractory Mediastinal Gray-Zone Lymphoma

Mediastinal gray-zone lymphoma, nodular sclerosis classic Hodgkin lymphoma (cHL), and primary mediastinal B-cell lymphoma have overlapping clinical, histologic, and molecular features, including the frequency...

ENDEAVOR: Carfilzomib Increases Overall Survival Over Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma

Previous results from the phase III ENDEAVOR study showed that treatment with the proteasome inhibitor carfilzomib plus dexamethasone extended progression-free survival (PFS) in patients...

Investigating How Patients With Hemophilia Manage Pain

As the life expectancy of people with hemophilia has increased, patients are living longer with disease-associated pain, particularly in their joints. According to the...

Is Idarucizumab the First “Antidote” to a Direct Oral Anticoagulant?

Idarucizumab “rapidly and completely” reversed the blood-thinning effects of the direct oral anticoagulant dabigatran in patients who had uncontrolled bleeding or were about to...

Can Gilteritinib Overcome FLT3 Inhibition Resistance in Patients With FLT3-Mutated AML?

Treatment with the oral FLT3/AXL inhibitor gilteritinib showed consistent FLT3 inhibition and high response rates in patients with FLT3-mutated, relapsed or refractory acute myeloid...

Study Finds Low Incidence of Intracranial Bleeding With Preventive Low-Dose Aspirin

The protective effect of low-dose aspirin against ischemic cardiovascular (CV) events and colorectal cancer (CRC) appears to outweigh the risks of major bleeding, including...

Randomized Study of Darbepoetin Alfa Shows Modest Reduction in RBC Transfusions in Patients With...

Treatment with the erythropoiesis-stimulating agent (ESA) darbepoetin alfa can reduce the need for red blood cell (RBC) transfusions in patients with lower-risk myelodysplastic syndromes...
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Current Issue

October 2017, Volume 3, Issue 12

This issue features a look at hospital ranking systems, the risks and benefits of opioids for pain management, and more.