Literature Scan

Literature Scan

New and noteworthy research from the medial literature landscape

Lenalidomide Maintenance Therapy Related to More Secondary Primary Malignancies in Older Adults

Wednesday, March 1st, 2017
Results from the Myeloma XI trial presented at the 2016 ASH Annual Meeting supported the use of lenalidomide as maintenance therapy for patients with...

Investigating Clonal Dynamics of Different Mutations in Myelodysplastic Syndromes

Wednesday, March 1st, 2017
In a whole-exome sequencing (WES) and targeted deep sequencing study published in Nature Genetics, researchers identified several biomarkers that could improve diagnosis and therapy...

TP53 Mutation Status Predicts Response to Decitabine for Patients With Acute Myeloid Leukemia...

Tuesday, February 28th, 2017
Patients with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) who have unfavorable-risk cytogenetic abnormalities and TP53 mutations responded to treatment with decitabine, according...

Is It Safe to Eliminate CHOP Consolidation Therapy for Patients With CD20+ Post-Transplant Lymphoproliferative...

Thursday, February 2nd, 2017
Results from the phase II PTLD-1 (Sequential Treatment of CD20-Positive Post-Transplant Lymphoproliferative Disorder) trial established sequential treatment with four cycles of weekly rituximab followed...

Severe Fatigue Affects Survival and Social Reintegration for Hodgkin Lymphoma Survivors

Thursday, February 2nd, 2017
Approximately 40 percent of patients with Hodgkin lymphoma (HL) experience persistent fatigue, a chronic symptom that can affect patients years after successful treatment. In...

Fludarabine + Busulfan: Improving Treatment-Related Mortality without Compromising Conditioning Intensity in High-Risk Multiple Myeloma

Monday, January 23rd, 2017
A myeloablative conditioning regimen consisting of fludarabine and busulfan was safe and effective in patients with high-risk multiple myeloma undergoing allogeneic hematopoietic cell transplantation...

Enoxaparin Does Not Prevent Placenta-Mediated Complications in Pregnant Women With Severe Preeclampsia

Tuesday, January 17th, 2017
Pregnant women who have severe preeclampsia (a disease characterized by impaired vascular response to placentation) before 34 weeks of pregnancy are at an increased...

Randomized Trial Finds Rivaroxaban a Safer Option Than Warfarin for Patients With Atrial Fibrillation...

Tuesday, January 17th, 2017
The “triple-therapy” anticoagulation regimen (consisting of a vitamin K antagonist plus dual antiplatelet therapy with a P2Y12 inhibitor and aspirin) has been...

Greater Survival and Response Rates with Bendamustine-Rituximab than Fludarabine-Rituximab in Patients with Non-Hodgkin Lymphoma...

Monday, January 2nd, 2017
The combination of bendamustine and rituximab (BR) resulted in superior overall response rates (ORR) and complete response (CR) rates, as well as progression-free survival...

Lenalidomide Shows Some Antitumor Activity in Patients With Relapsed or Recurrent Adult T-Cell Leukemia/Lymphoma

Thursday, December 29th, 2016
Patients with adult T-cell leukemia/lymphoma (ATLL) that is resistant to chemotherapeutic regimens have few treatment options. Following a phase I study determining the maximum-tolerated...
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Current Issue

March 2017, Volume 3, Issue 4

This issue takes a look at diversity in the medical education system, provides a hematology drug pipeline update, and more.