Written in Blood

Written in Blood

Research from recent issues of Blood

Can Pomalidomide Plus Dexamethasone “Rescue” Patients With Relapsed/ Refractory Amyloid Light-Chain Amyloidosis?

Tuesday, March 28th, 2017
Patients with amyloid light-chain (AL) amyloidosis are often treated upfront with combinations of alkylating agents and bortezomib; when they don’t respond to this regimen...

Encouraging Trends in Six-Month Mortality in Amyloid Light-Chain Amyloidosis

Tuesday, March 28th, 2017
With recent advances in diagnosis, treatment, and response assessment, clinicians have observed a significant decrease in six-month mortality (p<0.001) among patients with amyloid light-chain...

Can Podoplanin Explain the Connection Between Brain Tumors and Venous Thromboembolism?

Tuesday, March 28th, 2017
Podoplanin, a sialomucin-like glycoprotein that can induce blood platelet activation, is frequently expressed by primary brain tumors. Its overexpression can contribute to a greater...

Choosing Between Strategies for Managing Fetal or Neonatal Alloimmune Thrombocytopenia

Wednesday, March 1st, 2017
For women diagnosed with fetal and neonatal alloimmune thrombocytopenia (FNAIT), a noninvasive strategy of weekly intravenous immunoglobulin infusion (IVIg) and corticosteroids could help prevent...

Self-Reporting Significantly Overestimates Treatment Adherence in Pediatric Patients With Acute Lymphocytic Leukemia

Wednesday, March 1st, 2017
Maintenance therapy with oral 6-mercaptopurine (6MP) for pediatric patients with acute lymphocytic leukemia (ALL) is crucial for maintaining a durable remission, and poor adherence...

Radiation Dose and Use of Anthracyclines Increase Risk of Heart Failure in Hodgkin Lymphoma...

Wednesday, March 1st, 2017
Previous studies have linked mediastinal radiotherapy (RT) and/or anthracycline-containing chemotherapy with increased risk of coronary heart disease, valvular heart disease, and heart failure (HF)...

Report Questions the Validity of Rivaroxaban Trial

Friday, February 24th, 2017
An investigation by the British Journal of Medicine (BMJ) has raised questions about the validity of the pivotal ROCKET-AF trial, the results of which formed the...

Assessing Lenalidomide Plus Rituximab for Patients With MALT Lymphoma

Thursday, February 2nd, 2017
Patients with advanced mucosa-associated lymphoid tissue (MALT) lymphoma are often treated with chemotherapy-based regimens; however, because of the indolent course of the disease, researchers...

Where Does Clofarabine Fit in the Treatment of Patients With Acute Myeloid Leukemia?

Thursday, February 2nd, 2017
Adding clofarabine – a second-generation nucleoside analogue – to a standard induction regimen reduced the risk of relapse for patients with newly diagnosed acute...

Long-Term Analysis Identifies Encouraging Trends in Hemophilia A Care

Thursday, February 2nd, 2017
From 1999 to 2010, bleeding events among U.S. patients with hemophilia A have dropped dramatically, coinciding with a marked increase in the use of...

Current Issue

April 2017, Volume 3, Issue 5

This issue examines the art and science of myeloma drug sequencing, Mikkael Sekeres' letter to the ABIM, highlights from the 16th International Myeloma Workshop, and more.