Bleeding Disorders

Bleeding Disorders

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

Gene Therapy for Hemophilia: Progress and Setbacks

As the FDA delayed the approval of the world’s first gene therapy for hemophilia A, companies forged ahead with phase III trials to gather...

NIH Awards $1.5M to Study rHEALTH’s Fingerstick Hemophilia Test

The National Institutes of Health (NIH) has awarded $1.5 million to continue development of diagnostic company rHEALTH’s fingerstick blood test for monitoring factor VIII...

New Rules of the Road in TTP Management

In July 2020, the International Society on Thrombosis and Haemostasis (ISTH) issued its first-ever guidelines for the treatment of thrombotic thrombocytopenic purpura (TTP), helping...

The Year in FDA Approvals

Here, we review recent therapies approved by the U.S. Food and Drug Administration for the treatment of red blood cell and iron disorders, including...
On location

Investigating Tyrosine Kinase Inhibitors for ITP

In two presentations presented at EHA25 Virtual, the 25th European Hematology Association Annual Congress, investigators shared updates on two kinase inhibitors for the treatment...

Tranexamic Acid for Gastrointestinal Bleeding: Time to HALT-IT?

Although tranexamic acid reduces the risks of surgical bleeding and bleeding-related death in patients with trauma, it does not reduce risk of death from...
On location

ADAMTS13 Activity Levels Predict iTTP Recurrence

A study presented at the International Society on Thrombosis and Haemostasis (ISTH) 2020 Virtual Congress confirms the value of longitudinal quarterly assessment of ADAMTS13...
On location

Studies Confirm Long-Term Benefit of Gene Therapy for Hemophilia A

In two studies presented at the International Society on Thrombosis and Haemostasis (ISTH) 2020 Virtual Congress, gene therapies for hemophilia A demonstrated durable increases...
WIB_icon

Small Retrospective Study Suggests Thrombopoietin Receptor Agonists Are Safe, Likely Effective for ITP During...

Preliminary findings from an observational multicenter study suggest that temporary off-label use of thrombopoietin receptor agonists (TPO-RAs) for the treatment of severe and/or refractory...
On location

Extended Half-Life Factor VIII Fusion Protein Effective in Previously Untreated Hemophilia A

The use of extended half-life recombinant factor VIII Fc fusion protein (rFVIIIFc) appeared to be safe and effective in young boys with previously untreated...
Advertisement

Current Issue

Mid-January 2021 Annual Meeting Edition

This issue features highlights from the 2020 ASH Annual Meeting, a look at doctor-patient gifting customs around the world, and more.

Block title