Bleeding Disorders

Bleeding Disorders

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

U.K. Denying Benefit to Patients With Sickle Cell Disease

The U.K. government has been withholding personal independence payments (PIPs) from patients with sickle cell disease because the condition does not fit government criteria...
Sickle cell anemia

Voxelotor Increases Hemoglobin, Decreases Hemolysis in Patients With Sickle Cell Disease

A report from the phase III HOPE trial found that once-daily voxelotor led to greater increases in hemoglobin (Hb) levels and larger reductions in...

Bluebird Bio Wins European Approval for Beta Thalassemia Gene Therapy

Bluebird Bio’s one-time gene therapy, Zynteglo, has been cleared by E.U. regulators for the treatment of beta thalassemia in patients aged 12 and older....
On location

Erythropoietin Increases Hemoglobin and Reticulocyte Counts in Patients with Treatment-Refractory AIHA

In patients with autoimmune hemolytic anemia (AIHA) unresponsive to ongoing and/or prior therapies, treatment with erythropoietin (EPO) effectively increased hemoglobin (Hb) and reticulocyte counts,...
On location

Evaluating Rozanolixizumab in Primary Immune Thrombocytopenia

Rozanolixizumab, at doses ranging from 4 to 15 mg/kg, induced platelet responses in patients with primary immune thrombocytopenia (ITP), according to an interim analysis...

FDA Approves First Anticoagulant for Pediatric Patients

The FDA approved dalteparin sodium, administered as a subcutaneous injection, to reduce the recurrence of symptomatic venous thromboembolism (VTE) in pediatric patients (≥1 month). Dalteparin...
WIB_icon

Study Finds Urgent Need for Sickle Cell Disease Screening Among African Refugees in Italy

Most refugees who arrive at the Mediterranean coast of Italy and other southern European countries are leaving areas where sickle cell disease (SCD) is...

FDA Expands Avatrombopag’s Indication for Chronic Immune Thrombocytopenia

The U.S. Food and Drug Administration (FDA) granted approval to a supplemental new drug application for avatrombopag, expanding its use to include the treatment...
You Make the Call

How does triple X syndrome interact with Fanconi anemia?

This month, Joanne Kurtzberg, MD, discusses allogeneic hematopoietic cell transplantation in a patient with Fanconi anemia. And don't forget to check out next month's clinical...

India Sees Decline in Cases of Severe Anemia

India is home to one-quarter of patients with severe anemia, but a new report from the country’s Health Management Information System found that incidence...
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Current Issue

August 2019, Volume 5, Issue 10

August 2019, Volume 5, Issue 10

This issue features a debate about gun control as a health care issue, a look at blood services in Israel and Palestine, and more.