Bleeding Disorders

Bleeding Disorders

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

FDA Approves New Hemophilia A Drug

The U.S. Food and Drug Administration (FDA) has approved emicizumab-kxwh for the treatment of adult and pediatric patients with hemophilia A without factor VIII...
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Mapping Silent Cerebral Infarcts in Children With Sickle Cell Anemia

Children with sickle cell anemia (SCA) are at risk of developing cerebral ischemia, including a high prevalence of silent cerebral infarcts (SCI), which can...

LentiGlobin Gene Therapy Possibly Safe for Severe Sickle Cell Disease

Interim data from a phase I study of LentiGlobin BB305 in patients with severe sickle cell disease (SCD) suggest that the gene therapy was...

Breakthroughs in Gene Therapy for Hemophilia

Gene therapy for hemophilia is here – and it’s working. The field is advancing at a steady clip: Results from recent trials of this...

How Should We Treat Pregnant Women With Iron Deficiency?

Iron deficiency is prevalent among pregnant women, as maternal iron is used to supply the needs of the fetus and placenta, and additional iron...

American Society of Hematology’s Guidelines for Venous Thromboembolism and von Willebrand Disease

In 2018, the American Society of Hematology (ASH) has continued its efforts to develop and publish evidence-based clinical practice guidelines to help practicing hematologists...

Oral L-Glutamine Powder Lowers Frequency of Sickle Cell–Related Pain Episodes

Oral L-glutamine powder, with or without hydroxyurea, reduced the number of pain events experienced by children and adults with sickle cell disease (SCD), compared...

Lusutrombopag Approved for Thrombocytopenia in Chronic Liver Disease

The U.S. Food and Drug Administration has approved lusutrombopag for the treatment of thrombocytopenia in adults with chronic liver disease who are scheduled to...

How Do Patient and Physician Attitudes Drive Choices in Antiplatelet Therapy for Thrombocytopenia?

Patients with a hematologic malignancy and thrombocytopenia typically are treated with antiplatelet drugs, but there is little information to help clinicians balance the potential...

ASH to Launch SCD Clinical Trials Network

The American Society of Hematology (ASH) has announced the creation of a sickle cell disease (SCD) clinical trials network to accelerate the development of...
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Current Issue

October 2018, Volume 4, Issue 12

This issue features a look at the Right to Try debate, a breakdown of how epigenetics are used in hematology, and more.