Bleeding Disorders

Bleeding Disorders

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

WIB_icon

Observation Versus Immunoglobulin Therapy in Children With Chronic ITP

Compared with observation, treatment with intravenous immunoglobulin (IVIg) did not prevent the risk of developing chronic immune thrombocytopenia purpura (ITP) in children newly diagnosed...

Mehdi Hamadani Named Editor of ASH News Daily 2018, and more

Mehdi Hamadani Named Editor of ASH News Daily 2018  Mehdi Hamadani, MD, has been named the 2018 Editor-in- Chief of ASH News Daily, the official...

Plasma or Recombinant Products for Hemophilia?

For the past half-century, plasma products have been the mainstay for the treatment of patients with hemophilia. In the 1950s, hematologists used large volumes...
WIB_icon

Can AMT-060 Gene Therapy FIX Hemophilia B?

After a single infusion of AMT-060 (an adeno-associated virus-5 vector carrying a corrected human factor IX gene), patients with hemophilia B experienced...

Voxelotor: A New Option for Young Patients With Sickle Cell Disease?

Treatment with the hemoglobin S polymerization inhibitor voxelotor led to “a remarkable increase in hemoglobin levels” in young patients with sickle cell disease (SCD),...

Improving Pain Management in Patients With Sickle Cell Disease

Sickle cell disease (SCD) is associated with debilitating acute and chronic pain that can occur without warning, frequently sending people to the emergency department...

First Successful Gene Therapy Performed for Hemophilia A

In an ongoing phase I/II study of patients with hemophilia A, those who received a single infusion of BMN 270 (an adeno-associated virus serotype...

Delaying Treatment Reduces Survival Benefits of Antifibrinolytics in Patients With Acute Severe Bleeding

Administration of antifibrinolytic agents, such as tranexamic acid, reduces patients’ risk of death from trauma-related or postpartum bleeding, but delaying time to treatment for...

Emicizumab-kxwh Approved by FDA for Patients With Hemophilia A and Inhibitors

The U.S. Food and Drug Administration approved the first-in-class emicizumab-kxwh for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult...

Anticoagulation During Pregnancy

Because of physiologic changes during pregnancy, the risk of venous thromboembolism (VTE) is approximately five to 10 times higher than during non-pregnancy, and the...
Advertisement

Current Issue

August 2018, Volume 4, Issue 10

This issue features a look at direct-to-consumer pharmaceutical advertising, advice to graduating hematologists, and more.