Focus on Classical Hematology (Volume 5, Issue 12.1)

October 2019 Special Edition

Volume 5, Issue 12.1

This supplement explores new treatment options for hemophilia, gene therapy in nonmalignant hematologic disorders, and more.

Table of Contents

October 2019 Special Edition

Breakthroughs for Bleeding: Updates in Treating and Managing Hemophilia

Tuesday, October 1st, 2019
In 1982, the gene encoding factor IX (FIX) was cloned, followed by the cloning of the factor VIII (FVIII) gene in 1984. The events...

What Does the Future Hold for Gene Therapy in Nonmalignant Hematology?

Tuesday, October 1st, 2019
The human genome contains about 25,000 genes that encode myriad proteins that drive the processes necessary for life. But disruptions, deletions, and mutations can...

Representing Hemostasis and Thrombosis: An Interview With Roy Silverstein, MD

Tuesday, October 1st, 2019
2019 American Society of Hematology (ASH) President Roy Silverstein, MD, speaks about the goals of the ASH Working Group on Hemostasis and Thrombosis. What is...

October 2019 Special Edition

Higher Bleeding Risk With Higher Peak Direct Oral Anticoagulant Levels Suggests Need for More...

Tuesday, October 1st, 2019
A study of patients with nonvalvular atrial fibrillation (NVAF) who were receiving a direct oral anticoagulant (DOAC) found that bleeding complications were more frequent...

Male Sex, Factor V Leiden Mutation Increase Recurrent VTE Risk After First Cerebral Venous...

Tuesday, October 1st, 2019
A new study found that male sex and factor V Leiden mutation were associated with a higher risk of recurrent venous thromboembolism (VTE) after...

Testing the Testing Tool: ISTH Bleeding Assessment Accurately Predicts Patients With Platelet Function Disorders

Tuesday, October 1st, 2019
In patients with suspected platelet function disorders, the International Society on Thrombosis and Hemostasis bleeding assessment tool (ISTH-BAT) proved to be a useful instrument...

IV Iron Superior to Oral Iron for Managing Postpartum Anemia

Tuesday, October 1st, 2019
For women with postpartum anemia, treatment with intravenous (IV) iron was associated with higher hemoglobin concentrations at six weeks than oral iron, according to...

October 2019 Special Edition

On location

Examining Pregnancy Outcomes in Eculizumab-Treated Women With Atypical Hemolytic Uremic Syndrome

Tuesday, October 1st, 2019
Women with atypical hemolytic uremic syndrome (aHUS) treated with eculizumab have similar pregnancy outcomes to women who were not treated with eculizumab, according to...
On location

Patients With Hemophilia B Report Poor Bleeding Control With Extended Half-Life Factor IX Products

Tuesday, October 1st, 2019
Extended half-life factor IX (FIX) products have been designed to prolong the time between clotting factor injections for patients with hemophilia B, but an...

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