Calculating the Costs of Clinical Trials

Patients eager to contribute to research may not be fully aware of the hidden costs of trial participation Of the three potential risks of participating in a clinical trial listed on the National Institutes of...

Online Exclusives

Canadian Government and U.S. Pharmaceutical Industry Push Back Against Drug Imports

President Donald Trump’s plan to reduce drug costs in the U.S. by importing prescription drugs from Canada is facing opposition from the Canadian government...

Trump Backs Off Medicare Drug Price Negotiations Plan

After campaigning on a promise to negotiate drug prices for Medicare with pharmaceutical companies, President Donald Trump has backed off the idea, publicly criticizing...

News

From the Blood Journals

Patients’ Humoral Immunity Is Preserved, With Low Rates of Viral Infections,...

The two commercially available chimeric antigen receptor (CAR) T-cell products both target cells expressing the CD19 antigen, which is present on malignant and nonmalignant...
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Emicizumab Lowers Bleeding Rates in Children With Hemophilia A and Inhibitors

Once-weekly treatment with emicizumab prophylaxis led to low bleeding rates in children with hemophilia A and factor VIII (FVIII) inhibitors, with more than three-quarters...

Multimedia

Saad Usmani: Adding Daratumumab to Carfilzomib + Dexamethasone Extends PFS

Saad Usmani, MD, MBBS, shares findings from the CANDOR trial, in which the three-drug combination reduced the risk of disease progression or death by...

Stephen Schuster: Mosunetuzumab Leads to Durable Complete Remissions in Non-Hodgkin Lymphoma

Patients with both indolent and aggressive non-Hodgkin lymphomas responded to treatment with the monoclonal antibody, even those whose disease had not responded to CAR...

Patrick Brown: Is Blinatumomab a New Standard of Care Young Patients...

Patrick A. Brown, MD, discusses the results seen with blinatumomab as consolidation therapy in young patients with higher-risk, relapsed B-cell acute lymphocytic leukemia, where...

Megan Brown: Improving VWD Testing in Girls With Heavy Menstrual Bleeding

Megan C. Brown, MD, describes results from an emergency department–based initiative to improve the diagnostic accuracy of testing for von Willebrand disease in adolescents...

On Location

KTE-X19: A CAR T-Cell Option for Mantle Cell Lymphoma?

Ninety-three percent of patients with relapsed/refractory mantle cell lymphoma (MCL) responded to treatment with KTE-X19,...

Clarithromycin Improves Responses But Fails to Prolong Survival in Newly Diagnosed Myeloma

Adding clarithromycin to lenalidomide plus dexamethasone improved the response rate in patients with multiple myeloma...

Bomedemstat Reduces Symptom Burden for Patients With Myelofibrosis

Bomedemstat improved symptoms in most patients with myelofibrosis, with no dose-limiting toxicities or progressions to...

Mosunetuzumab Induces Durable Complete Remissions in Patients With B-Cell Non-Hodgkin Lymphoma

The bispecific monoclonal antibody mosunetuzumab, which targets CD3 and CD20, led to durable responses in...

DDGP Versus SMILE: Comparing Regimens for Extranodal Natural Killer T-Cell Lymphoma

In patients with extranodal natural killer T-cell lymphoma (ENKTL), treatment with the chemotherapy regimen of...

Romiplostim Improves Platelet Counts, Chemotherapy Adherence in Patients With Chemotherapy-Induced Thrombocytopenia

Patients with cancer who develop chemotherapy-induced thrombocytopenia (CIT) often require delays, reductions, or discontinuations of...

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ASH Directions

ASH Directions

ASH Commissions Study of U.S. Fellows, Honors Stanley Schrier with 2019 Exemplary Service Award,...

ASH Commissions 3-Year Longitudinal Study of U.S. Fellows The American Society of Hematology (ASH), in partnership with the Fitzhugh Mullan Institute for Health Workforce Equity...
ASH Directions

ASH Announces Three New Executive Committee Members, Free Childcare at the 2019 ASH Annual...

Congratulations to ASH’s Three New Executive Committee Members The American Society of Hematology (ASH) has announced the election of three new members to its Executive...

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The Society Pages

Nobel Prize Awarded for Discovery of How Cells Sense Oxygen, ASH Members Elected to...

Nobel Prize Awarded for Discovery of How Cells Sense Oxygen The Nobel Prize in physiology or medicine was awarded to scientists William G. Kaelin Jr.,...
The Society Pages

Remembering Thomas P. Stossel, CPRIT Awards $136 Million in 71 New Grants, and more

Remembering Thomas P. Stossel (1941 – 2019) Thomas P. Stossel, MD, former president of the American Society of Hematology (ASH), passed away unexpectedly on September...
The Society Pages

Remembering Stanley Schrier, John Hansen, and more

Remembering Stanley Schrier (1929 – 2019) Stanley Schrier, MD, a former American Society of Hematology (ASH) president who spent nearly 60 years at Stanford University’s...

Calculating the Costs of Clinical Trials

Patients eager to contribute to research may not be fully aware of the hidden costs of trial participation Of the three potential risks of participating...

Pediatric Hematology/Oncology: A Small Specialty Experiencing Big Changes

When Mona D. Shah, MD, MBA, finished her medical training in pediatric hematology/oncology in 2007, she estimated that most of her fellow trainees went...

Mainstreaming Alternative and Complementary Medicine

While some treatments for hematologic conditions such as sickle cell disease (SCD) and cancer, have been refined over time – increasing survival rates and...