Big Questions, Tough Answers

On October 17, 2017, Norman “Ned” Sharpless, MD, was sworn in as the 15th director of the National Cancer Institute (NCI), succeeding Harold E. Varmus, MD, who stepped down as director in March 2015,...

Online Exclusives

OxyContin Maker Stops Promoting Opioids

Purdue, the manufacturer of OxyContin, cut its sales forces in half and will stop promoting opioids to physicians. Its sales representatives will focus on...

CDC Programs at Risk

Funding for the Centers for Disease Control and Prevention’s (CDC) public health programs have been steadily scaled back by Congress. When the Tax Cuts...

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From the Blood Journals

Understanding Bone Disease and Fractures in Patients With MGUS

Patients with monoclonal gammopathy of undetermined significance (MGUS; a precursor to multiple myeloma and other lymphoproliferative disorders) are known to be at an...
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Can AMT-060 Gene Therapy FIX Hemophilia B?

After a single infusion of AMT-060 (an adeno-associated virus-5 vector carrying a corrected human factor IX gene), patients with hemophilia B experienced...

Multimedia

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Luc-Matthieu Fornecker, MD, PhD: Risks and Benefits of BV + AVD...

In the multicenter BREACH trial, adding brentuximab vedotin to AVD chemotherapy in patients with unfavorable, early-stage Hodgkin lymphoma led to higher rates of PET...
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Prithviraj Bose, MD: Optimizing Ruxolitinib With Sotatercept for Myelofibrosis

Dr. Bose discusses updated results from a phase II trial of sotatercept alone and with ruxolitinib, the only FDA-approved therapy for myelofibrosis, which also...
video

Jeanette K. Doorduijn, MD, PhD, and Samar Issa, MD: Does Rituximab...

Results from a randomized phase III trial examining rituximab in patients with central nervous lymphoma show that treatment with rituximab does not improve response...
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James N. Kochenderfer, MD: Advancing CAR T-Cell Therapy for Myeloma

Dr. Kochenderfer reports "very exciting" results from bb121, a new BCMA-targeting CAR T-cell therapy for treating patients with heavily pretreated myeloma, trending towards less...

On Location

A Preview of ASH’s Venous Thromboembolism Clinical Practice Guidelines

In November 2015, the American Society of Hematology (ASH) and the McMaster University GRADE Center...

Newly Approved Drugs for AML: How to Use Them in Practice

In 2017, the U.S. Food and Drug Administration (FDA) approved several therapies for the treatment...

Preliminary Results Show Flotetuzumab Well-Tolerated and Effective in Relapsed/Refractory AML and MDS

In early results from a phase I trial presented at the 2017 ASH Annual Meeting,...

Examining the Risk of Cardiovascular Disease–Related Mortality in Patients With and MDS/CMML

Patients with chronic myelomonocytic leukemia (CMML) and myelodysplastic syndromes (MDS) have a higher risk of...

Feeding the Fire: CHIP and Inflammation

Clonal hematopoiesis of indeterminate potential (CHIP), known as a “premalignant” state in the blood critical...

Treating MRD With Azacitidine in Patients With High-Risk AML and MDS

For 58 percent of patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) at...

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ASH Directions

Alexis Thompson Begins Term as 2018 ASH President, Course on Biosimilars Available, and more

Alexis A. Thompson, MD, MPH, Begins Term as 2018 ASH President Alexis A. Thompson, MD, MPH, a world-renowned expert in sickle cell disease and thalassemia,...

ASH Announces 2018 Scholar Award Recipients, New Ambassador Program, and more

Introducing the ASH Ambassador Program The ASH Ambassador Program supports recruitment and retention of trainees to hematology and to the Society, particularly underrepresented minorities, through...

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Amelia Langston Named Medical Director of Winship Cancer Network, Jordan Scott Orange Receives Edith...

Amelia Langston Named Medical Director of Winship Cancer Network Amelia (Amy) Langston, MD, joined the Winship Cancer Institute of Emory University as medical director of...

Fred Hutch Names New Director of HCT, UC San Diego School of Medicine Receives...

Barbara Savoldo Receives Grant From LLS for CAR T-Cell Research Barbara Savoldo, MD, PhD, assistant director of the Immunotherapy Program at the University of North...

National Academy of Medicine Announces New Hematology/Oncology Members, Winship Cancer Institute Earns NCI Designation,...

Emory University’s Winship Cancer Institute Earns NCI Designation Winship Cancer Institute of Emory University in Atlanta, Georgia, was granted comprehensive cancer center designation by the...

Conflict Resolution: Research Under the Influence

In an ideal world, medical advances would result from an altruistic pairing of outstanding translational science with well-designed and efficient clinical trials, and the...

Blood Donation: Separating Myth From Fact

After natural disasters and other tragic events, many people try to help by rushing to the nearest blood donation center. While there’s no denying...

Gun Violence: A Public Health Crisis

Does the oath to “do no harm” conflict with the right to bear arms? Issues related to gun violence and regulation are among the most...