Gun Violence: A Public Health Crisis

Does the oath to “do no harm” conflict with the right to bear arms? Issues related to gun violence and regulation are among the most divisive in the United States, with Americans split on the...

Online Exclusives

Following Brexit, EMA Selects New Headquarters

The headquarters of the European Medicines Agency (EMA) will relocate to Amsterdam from its location in London following the United Kingdom’s decision to exit...

No Easy Solution for Physician Burnout

Physician burnout – marked by emotional exhaustion, cynicism, and decreased effectiveness – is on the rise in the United States, with up to 54...

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From the Blood Journals

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Study Identifies Two Measures of Tumor Burden for Risk Stratification of...

The presence of bulky disease is commonly used as one factor in categorizing patients with early-stage Hodgkin lymphoma (HL) as having either favorable or...
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Examining Infection Risk in Patients Treated With Anti-CD19 CAR T-Cell Therapies

Management of the toxicities commonly associated with chimeric antigen receptor (CAR) T-cell therapy, including cytokine release syndrome (CRS) and neurotoxicity, can require stays in...

Multimedia

video

Geoffrey L. Uy, MD: Investigating Flotetuzumab in AML and MDS

Dr. Uy discusses preliminary results from a phase I trial of flotetuzumab, a CD123 x CD3 bispecific DART protein, in patients with relapsed/refractory acute...
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Gerald A. Soff, MD: Examining a New Indication for Romiplostim

Dr. Soff discusses results from a phase II study of romiplostim in treating patients with chemotherapy-induced thrombocytopenia. The agent led to high rates of...
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Remco Molenaar, MD, PhD: TET2 Mutations Predict Cardiovascular Risk in MDS...

Patients with myelodysplastic syndromes and chronic myelomonocytic leukemia and TET2 mutations have high risks of cardiovascular toxicity, suggesting that these patients might benefit from...
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Samir K. Ballas, MD: Sickle Cell Patients Are Innocent Victims of...

Patients with sickle cell disease (SCD) often take opioids to manage their pain, but use has not skyrocketed in the current opioid epidemic. Dr....

On Location

Palliative Care Use Infrequent in Patients with Hematologic Malignancies

Use of palliative care services among patients with hematologic malignancies is “sporadic at best,” and...

A New BTK Inhibitor on the Block: Zanubrutinib Demonstrates High Activity in Aggressive Non-Hodgkin Lymphomas

Zanubrutinib (BGB-3111) is a potent, highly specific, and irreversible Bruton tyrosine kinase (BTK) inhibitor that...

Phase I Trial Shows “Exciting” Results With Avapritinib in Advanced Systemic Mastocytosis

The oral KIT D816V inhibitor avapritinib (formerly known as BLU-285) could provide an alternative treatment...

Transfusion Dependence Delays Hospice Enrollment in Patients With Leukemia

Because many hospice organizations disallow life-extending transfusion support, transfusion dependence (TD) can pose a substantial...

Interim Results from the First-in-Human Trial of Antibody Drug Conjugate ADCT-402 in B-Cell Malignancies

In a first-in-human trial of loncastuximab tesirine, the CD19-targeting antibody drug conjugate (ADC) appeared to...

Preliminary Results Suggest Less-Frequent Emicizumab Dosing Feasible in Patients With Hemophilia A

In November 2017, the U.S. Food and Drug Administration (FDA) approved once-weekly dosing of the...

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ASH Directions

Harnessing Big Data’s Power, Updates to the Research Agenda, and more

Harnessing Big Data’s Power and Potential In keeping with the mission of helping hematologists conquer blood diseases worldwide, the American Society of Hematology (ASH) has...

ASH Announces New Executive Committee Members, ASH Members Visit Congress, and more

The Results Are In … ASH Announces 2018 Executive Committee Members ASH announced the election of four new members to its Executive Committee, the governing...

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Cancer Immunologist Receives New Innovator Award, Launch of Kids First Data Resource Center, and...

LSU Receives $10 Million Grant to Study Virus-Induced Cancers Louisiana State University (LSU) Health New Orleans received a five-year, $10 million grant from the National...

Remembering Harold Roberts and Tessa Holyoake, CRISPR Researchers Awarded Albany Medical Center Prize, and...

Remembering Harold R. Roberts, MD Harold R. Roberts, MD, a leader in the field of thrombosis and hemostasis and two-time American Society of Hematology (ASH)...

UC San Diego Researchers Receive Grant for CAR T-cell Therapy, New President at Seidman...

Theodoros N. Teknos Appointed President and Scientific Officer of University Hospitals Seidman Cancer Center Theodoros N. Teknos, MD, has been named the president and scientific...

Gun Violence: A Public Health Crisis

Does the oath to “do no harm” conflict with the right to bear arms? Issues related to gun violence and regulation are among the most...

What are Biosimilars?

Defining the new category and exploring physicians’ attitudes about biosimilars in the marketplace A growing number of biosimilars are making their way through the drug...

Demystifying Gene Editing With CRISPR

Gene editing has received a great deal of media attention in recently due to its potential for advancing science and treating disease. In a...